Vertebrate tracks are subject Eczema to a wide distribution of morphological types.A single trackmaker may be associated with a range of tracks reflecting individual pedal anatomy and behavioural kinematics mediated through substrate properties which may vary both in space and time.Accordingly, the same trackmaker can leave substantially different
In Vivo Experimental Study on the Enhancement of Optical Clearing Effect by Laser Irradiation in Conjunction with a Chemical Penetration Enhancer
The penetration of optical clearing agents (OCAs) is restricted by the natural barrier function of the stratum corneum (SC) of the skin, which can be breached by physical and chemical methods to enhance the transcutaneous delivery of OCAs.To breach the barrier function of SC, we carried out the in vivo experimental study to enhance the optical clea
Spontaneous resolution of large non-traumatic bilateral acute-on-chronic subdural hematoma
Background and importance: Chronic subdural hematomas are a frequently encountered neurosurgical pathology, especially in the elderly.They often require surgical evacuation, but recent studies Lip Pencil have shown good results with conservative treatment in selected cases.Clinical presentation: We report the case of a 72-year old patient that deve
A Combination of Blue Light at 460 nm and H2O2 for the Safe and Effective Eradication of Staphylococcus aureus in an Infected Mouse Skin Abrasion Model
Antibiotic-free approaches are more important than ever to address the rapidly growing problem of the antibiotic resistance crisis.The photolysis of the bacterial virulence factor staphyloxanthin using blue light at Games 460 nm (BL460 nm) has been found to effectively attenuate Staphylococcus aureus to chemical and physical agents.However, phototh
Bispecific engineered antibody domains (nanoantibodies) that interact noncompetitively with an HIV-1 neutralizing epitope and FcRn.
Libraries based on an isolated human immunoglobulin G1 (IgG1) constant domain 2 (CH2) have been previously diversified by random mutagenesis.However, native isolated CH2 is not very stable and the generation of many mutations could lead to an increase in immunogenicity.Recently, we demonstrated that engineering an additional disulfide bond and remo